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Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite
Traditional bottom-up mass spectrometry-based proteomics relies on the use of an enzyme, often trypsin, to generate small peptides (typically < 25 amino acids long). In top-down proteomics, proteins remain intact and are directly measured within the mass spectrometer. This technique, while inhere...
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| Udgivet i: | Methods Mol Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5373093/ https://ncbi.nlm.nih.gov/pubmed/28150248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6783-4_18 |
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