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The Ups and Downs of Repeated Cleavage and Internal Fragment Production in Top-Down Proteomics
Analysis of whole proteins by mass spectrometry, or top-down proteomics, has several advantages over methods relying on proteolysis. For example, proteoforms can be unambiguously identified and examined. However, from a gas-phase ion-chemistry perspective, proteins are enormous molecules that presen...
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| Publicado no: | J Am Soc Mass Spectrom |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5786485/ https://ncbi.nlm.nih.gov/pubmed/29038993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1823-8 |
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