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Chromatographic Efficiency and Selectivity in Top-down Proteomics of Histones

Histones are involved in epigenetic control of a wide variety of cellular processes through their multiple post-translational modifications. Their strongly cationic nature makes them challenging to separate with reversed-phase liquid chromatography coupled to mass spectrometry (RPLC-MS), where trifl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Chromatogr B Analyt Technol Biomed Life Sci
Egile Nagusiak: Zhou, Yiyang, Zhang, Ximo, Fornelli, Luca, Compton, Philip D., Kelleher, Neil, Wirth, Mary J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404389/
https://ncbi.nlm.nih.gov/pubmed/28076774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2016.12.027
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