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Chromatographic Efficiency and Selectivity in Top-down Proteomics of Histones
Histones are involved in epigenetic control of a wide variety of cellular processes through their multiple post-translational modifications. Their strongly cationic nature makes them challenging to separate with reversed-phase liquid chromatography coupled to mass spectrometry (RPLC-MS), where trifl...
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| Publicat a: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5404389/ https://ncbi.nlm.nih.gov/pubmed/28076774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2016.12.027 |
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