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Proton Transfer Charge Reduction Enables High-Throughput Top-Down Analysis of Large Proteoforms
Despite the recent technological advances in Fourier transform mass spectrometry (FTMS) instrumentation, top-down proteomics (TDP) is currently mostly applied to the characterization of proteoforms <30 kDa due to the poor performance of high-resolution FTMS for the analysis of larger proteoforms...
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| Publicado en: | Anal Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7008508/ https://ncbi.nlm.nih.gov/pubmed/31714757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b03925 |
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