Unabridged Analysis of Human Histone H3 by Differential Top-Down Mass Spectrometry Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression

Histones, and their modifications, are critical components of cellular programming and epigenetic inheritance. Recently, cancer genome sequencing has uncovered driver mutations in chromatin modifying enzymes spurring high interest how such mutations change histone modification patterns. Here, we app...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Zheng, Yupeng, Fornelli, Luca, Compton, Philip D., Sharma, Seema, Canterbury, Jesse, Mullen, Christopher, Zabrouskov, Vlad, Fellers, Ryan T., Thomas, Paul M., Licht, Jonathan D., Senko, Michael W., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Special Issue: Chromatin Biology and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813700/
https://ncbi.nlm.nih.gov/pubmed/26272979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.053819
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados