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In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L

BACKGROUND: Histone lysine methylation has a pivotal role in regulating the chromatin. Histone modifiers, including histone methyl transferases (HMTases), have clear roles in human carcinogenesis but the extent of their functions and regulation are not well understood. The NSD family of HMTases comp...

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Detalhes bibliográficos
Publicado no:BMC Struct Biol
Main Authors: Morishita, Masayo, Mevius, Damiaan, di Luccio, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280037/
https://ncbi.nlm.nih.gov/pubmed/25494638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-014-0025-x
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