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The catalytic domain of the histone methyltransferase NSD2/MMSET is required for the generation of B1 cells in mice
Humoral immunity in mammals relies on the function of two developmentally and functionally distinct B cell subsets - B1 and B2 cells. While B2 cells are responsible for the adaptive response to environmental antigens, B1 cells regulate the production of polyreactive and low affinity antibodies for i...
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| Publicado no: | FEBS Lett |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7722058/ https://ncbi.nlm.nih.gov/pubmed/32862441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13903 |
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