The catalytic domain of the histone methyltransferase NSD2/MMSET is required for the generation of B1 cells in mice

Humoral immunity in mammals relies on the function of two developmentally and functionally distinct B cell subsets - B1 and B2 cells. While B2 cells are responsible for the adaptive response to environmental antigens, B1 cells regulate the production of polyreactive and low affinity antibodies for i...

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Pubblicato in:FEBS Lett
Autori principali: Dobenecker, Marc-Werner, Marcello, Jonas, Becker, Annette, Rudensky, Eugene, Bhanu, Natarajan V., Carrol, Thomas, Garcia, Benjamin A., Prinjha, Rabinder, Yurchenko, Vyacheslav, Tarakhovsky, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722058/
https://ncbi.nlm.nih.gov/pubmed/32862441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13903
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