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Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa

Top-down proteomics is capable of identifying and quantitating unique proteoforms through the analysis of intact proteins. We extended the coverage of the label-free technique, achieving differential analysis of whole proteins <30 kDa from the proteomes of growing and senescent human fibroblasts....

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Detalles Bibliográficos
Publicado en:J Proteome Res
Main Authors: Durbin, Kenneth R., Fornelli, Luca, Fellers, Ryan T., Doubleday, Peter F., Narita, Masashi, Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794255/
https://ncbi.nlm.nih.gov/pubmed/26795204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b00997
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