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Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype

Primary diploid cells exit the cell cycle in response to exogenous stress or oncogene activation through a process known as cellular senescence. This cell-autonomous tumor-suppressive mechanism is also a major mechanism operative in organismal aging. To date, temporal aspects of senescence remain un...

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Pubblicato in:J Proteome Res
Autori principali: Doubleday, Peter F., Fornelli, Luca, Kelleher, Neil L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032038/
https://ncbi.nlm.nih.gov/pubmed/31940439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.9b00739
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