Glucocorticoids Suppress Selected Components of the Senescence-Associated Secretory Phenotype

Cellular senescence suppresses cancer by arresting the proliferation of cells at risk for malignant transformation. Recently, senescent cells were shown to secrete numerous cytokines, growth factors and proteases that can alter the tissue microenvironment and may promote age-related pathology. To id...

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Detalhes bibliográficos
Main Authors: Laberge, Remi-Martin, Zhou, Lili, Sarantos, Melissa R., Rodier, Francis, Freund, Adam, de Keizer, Peter L.J., Liu, Su, Demaria, Marco, Cong, Yu-Sheng, Kapahi, Pankaj, Desprez, Pierre-Yves, Hughes, Robert E., Campisi, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387333/
https://ncbi.nlm.nih.gov/pubmed/22404905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00818.x
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