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Lamin B1 loss is a senescence-associated biomarker

Cellular senescence is a potent tumor-suppressive mechanism that arrests cell proliferation and has been linked to aging. However, studies of senescence have been impeded by the lack of simple, exclusive biomarkers of the senescent state. Senescent cells develop characteristic morphological changes,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Freund, Adam, Laberge, Remi-Martin, Demaria, Marco, Campisi, Judith
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364172/
https://ncbi.nlm.nih.gov/pubmed/22496421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-10-0884
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