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Lamin B1 loss is a senescence-associated biomarker

Cellular senescence is a potent tumor-suppressive mechanism that arrests cell proliferation and has been linked to aging. However, studies of senescence have been impeded by the lack of simple, exclusive biomarkers of the senescent state. Senescent cells develop characteristic morphological changes,...

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Detalhes bibliográficos
Main Authors: Freund, Adam, Laberge, Remi-Martin, Demaria, Marco, Campisi, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364172/
https://ncbi.nlm.nih.gov/pubmed/22496421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-10-0884
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