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The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
Cellular senescence is a tumor-suppressive mechanism that permanently arrests cells at risk for malignant transformation. However, accumulating evidence shows that senescent cells can have deleterious effects on the tissue microenvironment. The most significant of these effects is the acquisition of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4166495/ https://ncbi.nlm.nih.gov/pubmed/20078217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-121808-102144 |
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