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A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen
Cellular senescence irreversibly arrests cell proliferation in response to oncogenic stimuli. Human cells develop a senescence-associated secretory phenotype (SASP), which increases the secretion of cytokines and other factors that alter the behavior of neighboring cells. We show here that “senescen...
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Main Authors: | , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Public Library of Science
2010
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820538/ https://ncbi.nlm.nih.gov/pubmed/20169192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009188 |
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