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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging

Mammalian cells can respond to damage or stress by entering a state of arrested growth and altered function termed cellular senescence. Several lines of evidence suggest that the senescence response suppresses tumorigenesis. Cellular senescence is also thought to contribute to aging, but the mechani...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Krtolica, Ana, Parrinello, Simona, Lockett, Stephen, Desprez, Pierre-Yves, Campisi, Judith
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The National Academy of Sciences 2001
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC59769/
https://ncbi.nlm.nih.gov/pubmed/11593017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211053698
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