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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging

Mammalian cells can respond to damage or stress by entering a state of arrested growth and altered function termed cellular senescence. Several lines of evidence suggest that the senescence response suppresses tumorigenesis. Cellular senescence is also thought to contribute to aging, but the mechani...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Krtolica, Ana, Parrinello, Simona, Lockett, Stephen, Desprez, Pierre-Yves, Campisi, Judith
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59769/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11593017/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.211053698
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