Fragmentation of Integral Membrane Proteins in the Gas Phase

Por Skinner, Owen S., Catherman, Adam D., Early, Bryan P., Thomas, Paul M., Compton, Philip D., Kelleher, Neil L.
Publicado em 2014

Evaluation of the Compact High-Field Orbitrap for Top-Down Proteomics of Human Cells

Por Ahlf, Dorothy R., Compton, Philip D., Tran, John C., Early, Bryan P., Thomas, Paul M., Kelleher, Neil L.
Publicado em 2012

The C-Score: A Bayesian Framework to Sharply Improve Proteoform Scoring in High-Throughput Top Down Proteomics

Por LeDuc, Richard D., Fellers, Ryan T., Early, Bryan P., Greer, Joseph B., Thomas, Paul M., Kelleher, Neil L.
Publicado em 2014

ProSight Lite: Graphical Software to Analyze Top-Down Mass Spectrometry Data

Por Fellers, Ryan T., Greer, Joseph B., Early, Bryan P., Yu, Xiang, LeDuc, Richard D., Kelleher, Neil L., Thomas, Paul M.
Publicado no Proteomics (2015)

Top Down Proteomics of Human Membrane Proteins from Enriched Mitochondrial Fractions

Por Catherman, Adam D., Li, Mingxi, Tran, John C., Durbin, Kenneth R., Compton, Philip D., Early, Bryan P., Thomas, Paul M., Kelleher, Neil L.
Publicado em 2013

Large-scale Top-down Proteomics of the Human Proteome: Membrane Proteins, Mitochondria, and Senescence

Por Catherman, Adam D., Durbin, Kenneth R., Ahlf, Dorothy R., Early, Bryan P., Fellers, Ryan T., Tran, John C., Thomas, Paul M., Kelleher, Neil L.
Publicado em 2013

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer

Por Fornelli, Luca, Durbin, Kenneth R., Fellers, Ryan T., Early, Bryan P., Greer, Joseph B., LeDuc, Richard D., Compton, Philip D., Kelleher, Neil L.
Publicado no J Proteome Res (2016)

Defining gas-phase fragmentation propensities of intact proteins during native top-down mass spectrometry

Por Haverland, Nicole A., Skinner, Owen S., Fellers, Ryan T., Tariq, Areeba A., Early, Bryan P., LeDuc, Richard D., Fornelli, Luca, Compton, Philip D., Kelleher, Neil L.
Publicado no J Am Soc Mass Spectrom (2017)

Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation

Por Shaw, Jared B., Li, Wenzong, Holden, Dustin D., Zhang, Yan, Griep-Raming, Jens, Fellers, Ryan T., Early, Bryan P., Thomas, Paul M., Kelleher, Neil L., Brodbelt, Jennifer S.
Publicado em 2013

ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry

Por Zamdborg, Leonid, LeDuc, Richard D., Glowacz, Kevin J., Kim, Yong-Bin, Viswanathan, Vinayak, Spaulding, Ian T., Early, Bryan P., Bluhm, Eric J., Babai, Shannee, Kelleher, Neil L.
Publicado em 2007

A Protease for Middle Down Proteomics

Por Wu, Cong, Tran, John C., Zamdborg, Leonid, Durbin, Kenneth R., Li, Mingxi, Ahlf, Dorothy R., Early, Bryan P., Thomas, Paul M., Sweedler, Jonathan V., Kelleher, Neil L.
Publicado em 2012

Applying Label-Free Quantitation to Top Down Proteomics

Por Ntai, Ioanna, Kim, Kyunggon, Fellers, Ryan T., Skinner, Owen S., Smith, Archer D., Early, Bryan P., Savaryn, John P., LeDuc, Richard D., Thomas, Paul M., Kelleher, Neil L.
Publicado em 2014

Ultraviolet Photodissociation for Characterization of Whole Proteins on a Chromatographic Time Scale

Por Cannon, Joe R., Cammarata, Michael B., Robotham, Scott A., Cotham, Victoria C., Shaw, Jared B., Fellers, Ryan T., Early, Bryan P., Thomas, Paul M., Kelleher, Neil L., Brodbelt, Jennifer S.
Publicado em 2014

Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts

Por Ntai, Ioanna, LeDuc, Richard D., Fellers, Ryan T., Erdmann-Gilmore, Petra, Davies, Sherri R., Rumsey, Jeanne, Early, Bryan P., Thomas, Paul M., Li, Shunqiang, Compton, Philip D., Ellis, Matthew J. C., Ruggles, Kelly V., Fenyö, David, Boja, Emily S., Rodriguez, Henry, Townsend, R. Reid, Kelleher, Neil L.
Publicado no Mol Cell Proteomics (2016)

Mapping Intact Protein Isoforms in Discovery Mode Using Top Down Proteomics

Por Tran, John C., Zamdborg, Leonid, Ahlf, Dorothy R., Lee, Ji Eun, Catherman, Adam D., Durbin, Kenneth R., Tipton, Jeremiah D., Vellaichamy, Adaikkalam, Kellie, John F., Li, Mingxi, Wu, Cong, Sweet, Steve M. M., Early, Bryan P., Siuti, Nertila, LeDuc, Richard D., Compton, Philip D., Thomas, Paul M., Kelleher, Neil L.
Publicado em 2011

An informatic framework for decoding protein complexes by top-down mass spectrometry

Por Skinner, Owen S., Havugimana, Pierre C., Haverland, Nicole A., Fornelli, Luca, Early, Bryan P., Greer, Joseph B., Fellers, Ryan T., Durbin, Kenneth R., Do Vale, Luis H. F., Melani, Rafael D., Seckler, Henrique S., Nelp, Micah T., Belov, Mikhail E., Horning, Stevan R., Makarov, Alexander A., LeDuc, Richard D., Bandarian, Vahe, Compton, Philip D., Kelleher, Neil L.
Publicado no Nat Methods (2016)

The first pilot project of the consortium for top-down proteomics: A status report

Por Dang, Xibei, Scotcher, Jenna, Wu, Si, Chu, Rosalie K., Tolić, Nikola, Ntai, Ioanna, Thomas, Paul M., Fellers, Ryan T., Early, Bryan P., Zheng, Yupeng, Durbin, Kenneth R., LeDuc, Richard D., Wolff, Jeremy J., Thompson, Christopher J., Pan, Jingxi, Han, Jun, Shaw, Jared B., Salisbury, Joseph P., Easterling, Michael, Borchers, Christoph H., Brodbelt, Jennifer S., Agar, Jeffery N., Paša-Tolić, Ljiljana, Kelleher, Neil L., Young, Nicolas L.
Publicado em 2014