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Top Down Proteomics of Human Membrane Proteins from Enriched Mitochondrial Fractions
The interrogation of intact integral membrane proteins has long been a challenge for biological mass spectrometry. Here, we demonstrate the application of Top Down mass spectrometry to whole membrane proteins below 60 kDa with up to 8 transmembrane helices. Analysis of enriched mitochondrial membran...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565750/ https://ncbi.nlm.nih.gov/pubmed/23305238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac3031527 |
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