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Evaluation of the Compact High-Field Orbitrap for Top-Down Proteomics of Human Cells

Mass spectrometry based proteomics generally seeks to identify and fully characterize protein species with high accuracy and throughput. Recent improvements in protein separation have greatly expanded the capacity of Top Down Proteomics (TDP) to identify a large number of intact proteins. To date, T...

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Detalhes bibliográficos
Main Authors: Ahlf, Dorothy R., Compton, Philip D., Tran, John C., Early, Bryan P., Thomas, Paul M., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437942/
https://ncbi.nlm.nih.gov/pubmed/22746247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr3004216
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