Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation

The top-down approach to proteomics offers compelling advantages due to the potential to provide complete characterization of protein sequence and post-translational modifications. Here we describe the implementation of 193 nm ultraviolet photodissociation (UVPD) in an Orbitrap mass spectrometer for...

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Main Authors: Shaw, Jared B., Li, Wenzong, Holden, Dustin D., Zhang, Yan, Griep-Raming, Jens, Fellers, Ryan T., Early, Bryan P., Thomas, Paul M., Kelleher, Neil L., Brodbelt, Jennifer S.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757099/
https://ncbi.nlm.nih.gov/pubmed/23697802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4029654
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