Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics

Top-down proteomics studies intact proteoform mixtures and offers important advantages over more common bottom-up proteomics technologies, as it avoids the protein inference problem. However, achieving complete molecular characterization of investigated proteoforms using existing technologies remain...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Fornelli, Luca, Srzentić, Kristina, Toby, Timothy K., Doubleday, Peter F., Huguet, Romain, Mullen, Christopher, Melani, Rafael D., dos Santos Seckler, Henrique, DeHart, Caroline J., Weisbrod, Chad R., Durbin, Kenneth R., Greer, Joseph B., Early, Bryan P., Fellers, Ryan T., Zabrouskov, Vlad, Thomas, Paul M., Compton, Philip D., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Technological Innovation and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000117/
https://ncbi.nlm.nih.gov/pubmed/31888965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR119.001638
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