Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts

Bottom-up proteomics relies on the use of proteases and is the method of choice for identifying thousands of protein groups in complex samples. Top-down proteomics has been shown to be robust for direct analysis of small proteins and offers a solution to the “peptide-to-protein” inference problem in...

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Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: Ntai, Ioanna, LeDuc, Richard D., Fellers, Ryan T., Erdmann-Gilmore, Petra, Davies, Sherri R., Rumsey, Jeanne, Early, Bryan P., Thomas, Paul M., Li, Shunqiang, Compton, Philip D., Ellis, Matthew J. C., Ruggles, Kelly V., Fenyö, David, Boja, Emily S., Rodriguez, Henry, Townsend, R. Reid, Kelleher, Neil L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762530/
https://ncbi.nlm.nih.gov/pubmed/26503891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.047480
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