An informatic framework for decoding protein complexes by top-down mass spectrometry

Efforts to map the human protein interactome have resulted in information about hundreds to thousands of multi-protein assemblies housed in public repositories, but the molecular characterization and stoichiometry of their protein subunits remains largely unknown. Here, we combined the CORUM and Uni...

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Pubblicato in:Nat Methods
Autori principali: Skinner, Owen S., Havugimana, Pierre C., Haverland, Nicole A., Fornelli, Luca, Early, Bryan P., Greer, Joseph B., Fellers, Ryan T., Durbin, Kenneth R., Do Vale, Luis H. F., Melani, Rafael D., Seckler, Henrique S., Nelp, Micah T., Belov, Mikhail E., Horning, Stevan R., Makarov, Alexander A., LeDuc, Richard D., Bandarian, Vahe, Compton, Philip D., Kelleher, Neil L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767540/
https://ncbi.nlm.nih.gov/pubmed/26780093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3731
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