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Refining the Structural Model of a Heterohexameric Protein Complex: Surface Induced Dissociation and Ion Mobility Provide Key Connectivity and Topology Information
[Image: see text] Toyocamycin nitrile hydratase (TNH) is a protein hexamer that catalyzes the hydration of toyocamycin to produce sangivamycin. The structure of hexameric TNH and the arrangement of subunits within the complex, however, have not been solved by NMR or X-ray crystallography. Native mas...
Shranjeno v:
| izdano v: | ACS Cent Sci |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical Society
2015
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4690985/ https://ncbi.nlm.nih.gov/pubmed/26744735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.5b00251 |
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