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Uncovering the Stoichiometry of Pyrococcus furiosus RNase P, a Multi-subunit Catalytic Ribonucleoprotein Complex, by Surface-Induced Dissociation and Ion Mobility-Mass Spectrometry
We demonstrate that surface-induced dissociation (SID) coupled with ion mobility-mass spectrometry (IM-MS) is a powerful tool for determining the stoichiometry and quaternary structure of a multi-subunit ribonucleoprotein (RNP) complex assembled in Mg(2+). We investigated here Pyrococcus furiosus (P...
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| Pubblicato in: | Angew Chem Int Ed Engl |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4552314/ https://ncbi.nlm.nih.gov/pubmed/25195671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201405362 |
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