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Dissecting functional cooperation among protein subunits in archaeal RNase P, a catalytic ribonucleoprotein complex

RNase P catalyzes the Mg(2)(+)-dependent 5′-maturation of precursor tRNAs. Biochemical studies on the bacterial holoenzyme, composed of one catalytic RNase P RNA (RPR) and one RNase P protein (RPP), have helped understand the pleiotropic roles (including substrate/Mg(2+) binding) by which a protein...

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Autores principales: Chen, Wen-Yi, Pulukkunat, Dileep K., Cho, I-Ming, Tsai, Hsin-Yue, Gopalan, Venkat
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001054/
https://ncbi.nlm.nih.gov/pubmed/20705647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq668
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