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Studies on Methanocaldococcus jannaschii RNase P reveal insights into the roles of RNA and protein cofactors in RNase P catalysis

Ribonuclease P (RNase P), a ribonucleoprotein (RNP) complex required for tRNA maturation, comprises one essential RNA (RPR) and protein subunits (RPPs) numbering one in bacteria, and at least four in archaea and nine in eukarya. While the bacterial RPR is catalytically active in vitro, only select e...

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Detalhes bibliográficos
Main Authors: Pulukkunat, Dileep K., Gopalan, Venkat
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475606/
https://ncbi.nlm.nih.gov/pubmed/18558617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn360
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