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Studies on Methanocaldococcus jannaschii RNase P reveal insights into the roles of RNA and protein cofactors in RNase P catalysis

Ribonuclease P (RNase P), a ribonucleoprotein (RNP) complex required for tRNA maturation, comprises one essential RNA (RPR) and protein subunits (RPPs) numbering one in bacteria, and at least four in archaea and nine in eukarya. While the bacterial RPR is catalytically active in vitro, only select e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pulukkunat, Dileep K., Gopalan, Venkat
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2008
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475606/
https://ncbi.nlm.nih.gov/pubmed/18558617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn360
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