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RNase P: role of distinct protein cofactors in tRNA substrate recognition and RNA-based catalysis

The Escherichia coli ribonuclease P (RNase P) has a protein component, termed C5, which acts as a cofactor for the catalytic M1 RNA subunit that processes the 5′ leader sequence of precursor tRNA. Rpp29, a conserved protein subunit of human RNase P, can substitute for C5 protein in reconstitution as...

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Detalhes bibliográficos
Main Authors: Sharin, Ela, Schein, Aleks, Mann, Hagit, Ben-Asouli, Yitzhak, Jarrous, Nayef
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201335/
https://ncbi.nlm.nih.gov/pubmed/16155184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki828
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