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Cooperative RNP assembly: Complementary rescue of structural defects by protein and RNA subunits of archaeal RNase P
RNase P is a ribonucleoprotein (RNP) complex that utilizes a Mg(2+)-dependent RNA catalyst to cleave the 5′-leader of precursor tRNAs (pre-tRNAs) and generate mature tRNAs. The bacterial RNase P protein (RPP) aids RNase P RNA (RPR) catalysis by promoting substrate binding, Mg(2+) coordination, and p...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3143260/ https://ncbi.nlm.nih.gov/pubmed/21683084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.05.012 |
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