Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry

[Image: see text] The emergence of complex protein therapeutics in general and monoclonal antibodies (mAbs) in particular have stimulated analytical chemists to develop new methods and strategies for their structural characterization. Mass spectrometry plays a key role in providing information on th...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: van der Burgt, Yuri E.M., Kilgour, David P. A., Tsybin, Yury O., Srzentić, Kristina, Fornelli, Luca, Beck, Alain, Wuhrer, Manfred, Nicolardi, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365908/
https://ncbi.nlm.nih.gov/pubmed/30571088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b04515
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