Monitoring glycation levels of a bispecific monoclonal antibody at subunit level by ultrahigh-resolution MALDI FT-ICR mass spectrometry

Bispecific monoclonal antibodies (BsAbs) are engineered proteins with multiple functionalities and properties. The “bi-specificity” of these complex biopharmaceuticals is a key characteristic for the development of novel and more effective therapeutic strategies. The high structural complexity of Bs...

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Publicado no:MAbs
Main Authors: Gstöttner, Christoph, Reusch, Dietmar, Haberger, Markus, Dragan, Irina, Van Veelen, Peter, Kilgour, David P. A., Tsybin, Yury O., van der Burgt, Yuri E. M., Wuhrer, Manfred, Nicolardi, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927770/
https://ncbi.nlm.nih.gov/pubmed/31630606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1682403
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