Progress in Top-Down Proteomics and the Analysis of Proteoforms

по Toby, Timothy K., Fornelli, Luca, Kelleher, Neil L.
Опубликовано в: Annu Rev Anal Chem (Palo Alto Calif) (2016)

Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype

по Doubleday, Peter F., Fornelli, Luca, Kelleher, Neil L.
Опубликовано в: J Proteome Res (2020)

Probing Asymmetric Charge Partitioning of Protein Oligomers during Tandem Mass Spectrometry

по Compton, Philip D., Fornelli, Luca, Kelleher, Neil L., Skinner, Owen S.
Опубликовано в: Int J Mass Spectrom (2015)

The Ups and Downs of Repeated Cleavage and Internal Fragment Production in Top-Down Proteomics

по Lyon, Yana A., Riggs, Dylan, Fornelli, Luca, Compton, Philip D., Julian, Ryan R.
Опубликовано в: J Am Soc Mass Spectrom (2017)

Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite

по DeHart, Caroline J., Fellers, Ryan T., Fornelli, Luca, Kelleher, Neil L., Thomas, Paul M.
Опубликовано в: Methods Mol Biol (2017)

Chromatographic Efficiency and Selectivity in Top-down Proteomics of Histones

по Zhou, Yiyang, Zhang, Ximo, Fornelli, Luca, Compton, Philip D., Kelleher, Neil, Wirth, Mary J.
Опубликовано в: J Chromatogr B Analyt Technol Biomed Life Sci (2016)

Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa

по Durbin, Kenneth R., Fornelli, Luca, Fellers, Ryan T., Doubleday, Peter F., Narita, Masashi, Kelleher, Neil L.
Опубликовано в: J Proteome Res (2016)

Mapping Proteoforms and Protein Complexes From King Cobra Venom Using Both Denaturing and Native Top-down Proteomics

по Melani, Rafael D., Skinner, Owen S., Fornelli, Luca, Domont, Gilberto B., Compton, Philip D., Kelleher, Neil L.
Опубликовано в: Mol Cell Proteomics (2016)

A comprehensive pipeline for translational top-down proteomics from a single blood draw

по Toby, Timothy K., Fornelli, Luca, Srzentić, Kristina, DeHart, Caroline J., Levitsky, Josh, Friedewald, John, Kelleher, Neil L.
Опубликовано в: Nat Protoc (2019)

Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS

по Fornelli, Luca, Damoc, Eugen, Thomas, Paul M., Kelleher, Neil L., Aizikov, Konstantin, Denisov, Eduard, Makarov, Alexander, Tsybin, Yury O.
Опубликовано 2012

Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry

по Melani, Rafael D., Srzentić, Kristina, Gerbasi, Vincent R., McGee, John P., Huguet, Romain, Fornelli, Luca, Kelleher, Neil L.
Опубликовано в: MAbs (2019)

Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry

по Savaryn, John Paul, Skinner, Owen S., Fornelli, Luca, Fellers, Ryan T., Compton, Philip D., Terhune, Scott S., Abecassis, Mike M., Kelleher, Neil L.
Опубликовано в: J Proteomics (2015)

Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer

по Fornelli, Luca, Ayoub, Daniel, Aizikov, Konstantin, Liu, Xiaowen, Damoc, Eugen, Pevzner, Pavel A., Makarov, Alexander, Beck, Alain, Tsybin, Yury O.
Опубликовано в: J Proteomics (2017)

Top-down proteomics: where we are, where we are going?

по Fornelli, Luca, Toby, Timothy K., Schachner, Luis F., Doubleday, Peter F., Srzentić, Kristina, DeHart, Caroline J., Kelleher, Neil L.
Опубликовано в: J Proteomics (2017)

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding

по Huang, Xiaoxiao, LeDuc, Richard D., Fornelli, Luca, Schunter, Alissa J., Bennett, Richard L., Kelleher, Neil L., Licht, Jonathan D.
Опубликовано в: J Biol Chem (2019)

Proton Transfer Charge Reduction Enables High-Throughput Top-Down Analysis of Large Proteoforms

по Huguet, Romain, Mullen, Christopher, Srzentić, Kristina, Greer, Joseph B., Fellers, Ryan T., Zabrouskov, Vlad, Syka, John E. P., Kelleher, Neil L., Fornelli, Luca
Опубликовано в: Anal Chem (2019)

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer

по Fornelli, Luca, Durbin, Kenneth R., Fellers, Ryan T., Early, Bryan P., Greer, Joseph B., LeDuc, Richard D., Compton, Philip D., Kelleher, Neil L.
Опубликовано в: J Proteome Res (2016)

Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques

по Fornelli, Luca, Srzentić, Kristina, Huguet, Romain, Mullen, Christopher, Sharma, Seema, Zabrouskov, Vlad, Fellers, Ryan T., Durbin, Kenneth R., Compton, Philip D., Kelleher, Neil L.
Опубликовано в: Anal Chem (2018)

Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry

по van der Burgt, Yuri E.M., Kilgour, David P. A., Tsybin, Yury O., Srzentić, Kristina, Fornelli, Luca, Beck, Alain, Wuhrer, Manfred, Nicolardi, Simone
Опубликовано в: Anal Chem (2018)

Defining gas-phase fragmentation propensities of intact proteins during native top-down mass spectrometry

по Haverland, Nicole A., Skinner, Owen S., Fellers, Ryan T., Tariq, Areeba A., Early, Bryan P., LeDuc, Richard D., Fornelli, Luca, Compton, Philip D., Kelleher, Neil L.
Опубликовано в: J Am Soc Mass Spectrom (2017)