Progress in Top-Down Proteomics and the Analysis of Proteoforms

di Toby, Timothy K., Fornelli, Luca, Kelleher, Neil L.
Pubblicato in Annu Rev Anal Chem (Palo Alto Calif) (2016)

Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype

di Doubleday, Peter F., Fornelli, Luca, Kelleher, Neil L.
Pubblicato in J Proteome Res (2020)

Probing Asymmetric Charge Partitioning of Protein Oligomers during Tandem Mass Spectrometry

di Compton, Philip D., Fornelli, Luca, Kelleher, Neil L., Skinner, Owen S.
Pubblicato in Int J Mass Spectrom (2015)

The Ups and Downs of Repeated Cleavage and Internal Fragment Production in Top-Down Proteomics

di Lyon, Yana A., Riggs, Dylan, Fornelli, Luca, Compton, Philip D., Julian, Ryan R.
Pubblicato in J Am Soc Mass Spectrom (2017)

Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite

di DeHart, Caroline J., Fellers, Ryan T., Fornelli, Luca, Kelleher, Neil L., Thomas, Paul M.
Pubblicato in Methods Mol Biol (2017)

Chromatographic Efficiency and Selectivity in Top-down Proteomics of Histones

di Zhou, Yiyang, Zhang, Ximo, Fornelli, Luca, Compton, Philip D., Kelleher, Neil, Wirth, Mary J.
Pubblicato in J Chromatogr B Analyt Technol Biomed Life Sci (2016)

Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa

di Durbin, Kenneth R., Fornelli, Luca, Fellers, Ryan T., Doubleday, Peter F., Narita, Masashi, Kelleher, Neil L.
Pubblicato in J Proteome Res (2016)

Mapping Proteoforms and Protein Complexes From King Cobra Venom Using Both Denaturing and Native Top-down Proteomics

di Melani, Rafael D., Skinner, Owen S., Fornelli, Luca, Domont, Gilberto B., Compton, Philip D., Kelleher, Neil L.
Pubblicato in Mol Cell Proteomics (2016)

A comprehensive pipeline for translational top-down proteomics from a single blood draw

di Toby, Timothy K., Fornelli, Luca, Srzentić, Kristina, DeHart, Caroline J., Levitsky, Josh, Friedewald, John, Kelleher, Neil L.
Pubblicato in Nat Protoc (2019)

Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS

di Fornelli, Luca, Damoc, Eugen, Thomas, Paul M., Kelleher, Neil L., Aizikov, Konstantin, Denisov, Eduard, Makarov, Alexander, Tsybin, Yury O.
Pubblicazione 2012

Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry

di Melani, Rafael D., Srzentić, Kristina, Gerbasi, Vincent R., McGee, John P., Huguet, Romain, Fornelli, Luca, Kelleher, Neil L.
Pubblicato in MAbs (2019)

Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry

di Savaryn, John Paul, Skinner, Owen S., Fornelli, Luca, Fellers, Ryan T., Compton, Philip D., Terhune, Scott S., Abecassis, Mike M., Kelleher, Neil L.
Pubblicato in J Proteomics (2015)

Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer

di Fornelli, Luca, Ayoub, Daniel, Aizikov, Konstantin, Liu, Xiaowen, Damoc, Eugen, Pevzner, Pavel A., Makarov, Alexander, Beck, Alain, Tsybin, Yury O.
Pubblicato in J Proteomics (2017)

Top-down proteomics: where we are, where we are going?

di Fornelli, Luca, Toby, Timothy K., Schachner, Luis F., Doubleday, Peter F., Srzentić, Kristina, DeHart, Caroline J., Kelleher, Neil L.
Pubblicato in J Proteomics (2017)

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding

di Huang, Xiaoxiao, LeDuc, Richard D., Fornelli, Luca, Schunter, Alissa J., Bennett, Richard L., Kelleher, Neil L., Licht, Jonathan D.
Pubblicato in J Biol Chem (2019)

Proton Transfer Charge Reduction Enables High-Throughput Top-Down Analysis of Large Proteoforms

di Huguet, Romain, Mullen, Christopher, Srzentić, Kristina, Greer, Joseph B., Fellers, Ryan T., Zabrouskov, Vlad, Syka, John E. P., Kelleher, Neil L., Fornelli, Luca
Pubblicato in Anal Chem (2019)

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer

di Fornelli, Luca, Durbin, Kenneth R., Fellers, Ryan T., Early, Bryan P., Greer, Joseph B., LeDuc, Richard D., Compton, Philip D., Kelleher, Neil L.
Pubblicato in J Proteome Res (2016)

Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques

di Fornelli, Luca, Srzentić, Kristina, Huguet, Romain, Mullen, Christopher, Sharma, Seema, Zabrouskov, Vlad, Fellers, Ryan T., Durbin, Kenneth R., Compton, Philip D., Kelleher, Neil L.
Pubblicato in Anal Chem (2018)

Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry

di van der Burgt, Yuri E.M., Kilgour, David P. A., Tsybin, Yury O., Srzentić, Kristina, Fornelli, Luca, Beck, Alain, Wuhrer, Manfred, Nicolardi, Simone
Pubblicato in Anal Chem (2018)

Defining gas-phase fragmentation propensities of intact proteins during native top-down mass spectrometry

di Haverland, Nicole A., Skinner, Owen S., Fellers, Ryan T., Tariq, Areeba A., Early, Bryan P., LeDuc, Richard D., Fornelli, Luca, Compton, Philip D., Kelleher, Neil L.
Pubblicato in J Am Soc Mass Spectrom (2017)