Progress in Top-Down Proteomics and the Analysis of Proteoforms

מאת Toby, Timothy K., Fornelli, Luca, Kelleher, Neil L.
הוצא לאור ב Annu Rev Anal Chem (Palo Alto Calif) (2016)

Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype

מאת Doubleday, Peter F., Fornelli, Luca, Kelleher, Neil L.
הוצא לאור ב J Proteome Res (2020)

Probing Asymmetric Charge Partitioning of Protein Oligomers during Tandem Mass Spectrometry

מאת Compton, Philip D., Fornelli, Luca, Kelleher, Neil L., Skinner, Owen S.
הוצא לאור ב Int J Mass Spectrom (2015)

The Ups and Downs of Repeated Cleavage and Internal Fragment Production in Top-Down Proteomics

מאת Lyon, Yana A., Riggs, Dylan, Fornelli, Luca, Compton, Philip D., Julian, Ryan R.
הוצא לאור ב J Am Soc Mass Spectrom (2017)

Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite

מאת DeHart, Caroline J., Fellers, Ryan T., Fornelli, Luca, Kelleher, Neil L., Thomas, Paul M.
הוצא לאור ב Methods Mol Biol (2017)

Chromatographic Efficiency and Selectivity in Top-down Proteomics of Histones

מאת Zhou, Yiyang, Zhang, Ximo, Fornelli, Luca, Compton, Philip D., Kelleher, Neil, Wirth, Mary J.
הוצא לאור ב J Chromatogr B Analyt Technol Biomed Life Sci (2016)

Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa

מאת Durbin, Kenneth R., Fornelli, Luca, Fellers, Ryan T., Doubleday, Peter F., Narita, Masashi, Kelleher, Neil L.
הוצא לאור ב J Proteome Res (2016)

Mapping Proteoforms and Protein Complexes From King Cobra Venom Using Both Denaturing and Native Top-down Proteomics

מאת Melani, Rafael D., Skinner, Owen S., Fornelli, Luca, Domont, Gilberto B., Compton, Philip D., Kelleher, Neil L.
הוצא לאור ב Mol Cell Proteomics (2016)

A comprehensive pipeline for translational top-down proteomics from a single blood draw

מאת Toby, Timothy K., Fornelli, Luca, Srzentić, Kristina, DeHart, Caroline J., Levitsky, Josh, Friedewald, John, Kelleher, Neil L.
הוצא לאור ב Nat Protoc (2019)

Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS

מאת Fornelli, Luca, Damoc, Eugen, Thomas, Paul M., Kelleher, Neil L., Aizikov, Konstantin, Denisov, Eduard, Makarov, Alexander, Tsybin, Yury O.
יצא לאור 2012

Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry

מאת Melani, Rafael D., Srzentić, Kristina, Gerbasi, Vincent R., McGee, John P., Huguet, Romain, Fornelli, Luca, Kelleher, Neil L.
הוצא לאור ב MAbs (2019)

Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry

מאת Savaryn, John Paul, Skinner, Owen S., Fornelli, Luca, Fellers, Ryan T., Compton, Philip D., Terhune, Scott S., Abecassis, Mike M., Kelleher, Neil L.
הוצא לאור ב J Proteomics (2015)

Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer

מאת Fornelli, Luca, Ayoub, Daniel, Aizikov, Konstantin, Liu, Xiaowen, Damoc, Eugen, Pevzner, Pavel A., Makarov, Alexander, Beck, Alain, Tsybin, Yury O.
הוצא לאור ב J Proteomics (2017)

Top-down proteomics: where we are, where we are going?

מאת Fornelli, Luca, Toby, Timothy K., Schachner, Luis F., Doubleday, Peter F., Srzentić, Kristina, DeHart, Caroline J., Kelleher, Neil L.
הוצא לאור ב J Proteomics (2017)

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding

מאת Huang, Xiaoxiao, LeDuc, Richard D., Fornelli, Luca, Schunter, Alissa J., Bennett, Richard L., Kelleher, Neil L., Licht, Jonathan D.
הוצא לאור ב J Biol Chem (2019)

Proton Transfer Charge Reduction Enables High-Throughput Top-Down Analysis of Large Proteoforms

מאת Huguet, Romain, Mullen, Christopher, Srzentić, Kristina, Greer, Joseph B., Fellers, Ryan T., Zabrouskov, Vlad, Syka, John E. P., Kelleher, Neil L., Fornelli, Luca
הוצא לאור ב Anal Chem (2019)

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer

מאת Fornelli, Luca, Durbin, Kenneth R., Fellers, Ryan T., Early, Bryan P., Greer, Joseph B., LeDuc, Richard D., Compton, Philip D., Kelleher, Neil L.
הוצא לאור ב J Proteome Res (2016)

Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques

מאת Fornelli, Luca, Srzentić, Kristina, Huguet, Romain, Mullen, Christopher, Sharma, Seema, Zabrouskov, Vlad, Fellers, Ryan T., Durbin, Kenneth R., Compton, Philip D., Kelleher, Neil L.
הוצא לאור ב Anal Chem (2018)

Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry

מאת van der Burgt, Yuri E.M., Kilgour, David P. A., Tsybin, Yury O., Srzentić, Kristina, Fornelli, Luca, Beck, Alain, Wuhrer, Manfred, Nicolardi, Simone
הוצא לאור ב Anal Chem (2018)

Defining gas-phase fragmentation propensities of intact proteins during native top-down mass spectrometry

מאת Haverland, Nicole A., Skinner, Owen S., Fellers, Ryan T., Tariq, Areeba A., Early, Bryan P., LeDuc, Richard D., Fornelli, Luca, Compton, Philip D., Kelleher, Neil L.
הוצא לאור ב J Am Soc Mass Spectrom (2017)