Mutation of Three Residues in the Third Intracellular Loop of the Dopamine D(2) Receptor Creates an Internalization-defective Receptor

Yazar: Clayton, Cecilea C., Donthamsetti, Prashant, Lambert, Nevin A., Javitch, Jonathan A., Neve, Kim A.
Yayımlandı J Biol Chem (2014)

What Can Crystal Structures of Aminergic Receptors Tell Us about Designing Subtype-Selective Ligands?

Yazar: Michino, Mayako, Beuming, Thijs, Donthamsetti, Prashant, Newman, Amy Hauck, Javitch, Jonathan A., Shi, Lei
Yayımlandı Pharmacol Rev (2015)

Using bioluminescent resonance energy transfer (BRET) to characterize agonist-induced arrestin recruitment to modified and unmodified G protein-coupled receptors (GPCRs)

Yazar: Donthamsetti, Prashant, Quejada, Jose Rafael, Javitch, Jonathan A., Gurevich, Vsevolod V., Lambert, Nevin A.
Yayımlandı Curr Protoc Pharmacol (2015)

Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor

Yazar: Donthamsetti, Prashant, Konrad, David B., Hetzler, Belinda, Fu, Zhu, Trauner, Dirk, Isacoff, Ehud Y.
Yayımlandı J Am Chem Soc (2021)

Amino Acid Architecture That Influences dNTP Insertion Efficiency in Y-Family DNA Polymerase V of E. coli

Yazar: Seo, Kwang Young, Yin, Jun, Donthamsetti, Prashant, Chandani, Sushil, Lee, Chui Hong, Loechler, Edward L.
Baskı/Yayın Bilgisi 2009

Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist

Yazar: Donthamsetti, Prashant C., Winter, Nils, Schönberger, Matthias, Levitz, Joshua, Stanley, Cherise, Javitch, Jonathan A., Isacoff, Ehud Y., Trauner, Dirk
Yayımlandı J Am Chem Soc (2017)

A Single Glycine in Extracellular Loop 1 Is the Critical Determinant for Pharmacological Specificity of Dopamine D2 and D3 Receptors

Yazar: Michino, Mayako, Donthamsetti, Prashant, Beuming, Thijs, Banala, Ashwini, Duan, Lihua, Roux, Thomas, Han, Yang, Trinquet, Eric, Newman, Amy Hauck, Javitch, Jonathan A., Shi, Lei
Baskı/Yayın Bilgisi 2013

Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor

Yazar: Donthamsetti, Prashant C., Broichhagen, Johannes, Vyklicky, Vojtech, Stanley, Cherise, Fu, Zhu, Visel, Meike, Levitz, Joshua L., Javitch, Jonathan A., Trauner, Dirk, Isacoff, Ehud Y.
Yayımlandı J Am Chem Soc (2019)

Development of a Rapid Insulin Assay by Homogenous Time-Resolved Fluorescence

Yazar: Farino, Zachary J., Morgenstern, Travis J., Vallaghe, Julie, Gregor, Nathalie, Donthamsetti, Prashant, Harris, Paul E., Pierre, Nicolas, Freyberg, Robin, Charrier-Savournin, Fabienne, Javitch, Jonathan A., Freyberg, Zachary
Yayımlandı PLoS One (2016)

Regional heterogeneity of D2-receptor signaling in the dorsal striatum and nucleus accumbens

Yazar: Marcott, Pamela F, Gong, Sheng, Donthamsetti, Prashant, Grinnell, Steven G., Nelson, Melissa N., Newman, Amy H, Birnbaumer, Lutz, Martemyanov, Kirill A, Javitch, Jonathan A, Ford, Christopher P
Yayımlandı Neuron (2018)

Arrestin recruitment to dopamine D2 receptor mediates locomotion but not incentive motivation

Yazar: Donthamsetti, Prashant, Gallo, Eduardo F., Buck, David C., Stahl, Edward L., Zhu, Ying, Lane, J. Robert, Bohn, Laura M., Neve, Kim A., Kellendonk, Christoph, Javitch, Jonathan A.
Yayımlandı Mol Psychiatry (2018)

Molecular Determinants of Selectivity and Efficacy at the Dopamine D3 Receptor

Yazar: Newman, Amy Hauck, Beuming, Thijs, Banala, Ashwini K., Donthamsetti, Prashant, Pongetti, Katherine, LaBounty, Alex, Levy, Benjamin, Cao, Jianjing, Michino, Mayako, Luedtke, Robert R., Javitch, Jonathan A., Shi, Lei
Baskı/Yayın Bilgisi 2012

Optical Control of Lysophosphatidic Acid Signaling

Yazar: Morstein, Johannes, Dacheux, Mélanie A., Norman, Derek D., Shemet, Andrej, Donthamsetti, Prashant C., Citir, Mevlut, Frank, James A., Schultz, Carsten, Isacoff, Ehud Y., Parrill, Abby L., Tigyi, Gabor J., Trauner, Dirk
Yayımlandı J Am Chem Soc (2020)

A new mechanism of allostery in a G protein-coupled receptor dimer

Yazar: Lane, J. Robert, Donthamsetti, Prashant, Shonberg, Jeremy, Draper-Joyce, Christopher J., Dentry, Samuel, Michino, Mayako, Shi, Lei, López, Laura, Scammells, Peter J., Capuano, Ben, Sexton, Patrick M., Javitch, Jonathan A., Christopoulos, Arthur
Baskı/Yayın Bilgisi 2014

The role of kinetic context in apparent biased agonism at GPCRs

Yazar: Klein Herenbrink, Carmen, Sykes, David A., Donthamsetti, Prashant, Canals, Meritxell, Coudrat, Thomas, Shonberg, Jeremy, Scammells, Peter J., Capuano, Ben, Sexton, Patrick M., Charlton, Steven J., Javitch, Jonathan A., Christopoulos, Arthur, Lane, J. Robert
Yayımlandı Nat Commun (2016)

High Affinity Dopamine D(3) Receptor (D(3)R)-Selective Antagonists Attenuate Heroin Self-Administration in Wild-Type but not D(3)R Knockout Mice

Yazar: Boateng, Comfort A., Bakare, Oluyomi M., Zhan, Jia, Banala, Ashwini K., Burzynski, Caitlin, Pommier, Elie, Keck, Thomas M., Donthamsetti, Prashant, Javitch, Jonathan A., Rais, Rana, Slusher, Barbara S., Xi, Zheng-Xiong, Newman, Amy Hauck
Yayımlandı J Med Chem (2015)

Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D(2)/D(3) Receptor Agonist Selectivity

Yazar: Zou, Mu-Fa, Keck, Thomas M., Kumar, Vivek, Donthamsetti, Prashant, Michino, Mayako, Burzynski, Caitlin, Schweppe, Catherine, Bonifazi, Alessandro, Free, R. Benjamin, Sibley, David R., Janowsky, Aaron, Shi, Lei, Javitch, Jonathan A., Newman, Amy Hauck
Yayımlandı J Med Chem (2016)

Towards understanding the structural basis of partial agonism at the dopamine D(3) receptor

Yazar: Michino, Mayako, Boateng, Comfort A., Donthamsetti, Prashant, Yano, Hideaki, Bakare, Oluyomi M., Bonifazi, Alessandro, Ellenberger, Michael P., Keck, Thomas M., Kumar, Vivek, Zhu, Clare, Verma, Ravi, Deschamps, Jeffrey R., Javitch, Jonathan A., Newman, Amy Hauck, Shi, Lei
Yayımlandı J Med Chem (2017)

Optical Control of Sphingosine-1-Phosphate Formation and Function

Yazar: Morstein, Johannes, Hill, Rose Z., Novak, Alexander J. E., Feng, Suihan, Norman, Derek D., Donthamsetti, Prashant C., Frank, James A., Harayama, Takeshi, Williams, Benjamin M., Parrill, Abby L., Tigyi, Gabor J., Riezman, Howard, Isacoff, Ehud Y., Bautista, Diana M., Trauner, Dirk
Yayımlandı Nat Chem Biol (2019)

New roles for dopamine D(2) and D(3) receptors in pancreatic beta cell insulin secretion

Yazar: Farino, Zachary J., Morgenstern, Travis J., Maffei, Antonella, Quick, Matthias, De Solis, Alain J., Wiriyasermkul, Pattama, Freyberg, Robin J., Aslanoglou, Despoina, Sorisio, Denise, Inbar, Benjamin P., Free, R. Benjamin, Donthamsetti, Prashant, Mosharov, Eugene V., Kellendonk, Christoph, Schwartz, Gary J., Sibley, David R., Schmauss, Claudia, Zeltser, Lori M., Moore, Holly, Harris, Paul E., Javitch, Jonathan A., Freyberg, Zachary
Yayımlandı Mol Psychiatry (2019)