Sandmeyer reaction repurposed for the site-selective, non-oxidizing radioiodination of fully-deprotected peptides: Studies on the endogenous opioid peptide α-neoendorphin

di Pickett, Julie E., Nagakura, Kunihiko, Pasternak, Anna R., Grinnell, Steven G., Majumdar, Susruta, Lewis, Jason S., Pasternak, Gavril W.
Pubblicazione 2013

Pharmacologic Characterization in the Rat of a Potent Analgesic Lacking Respiratory Depression, IBNtxA

di Grinnell, Steven G., Majumdar, Susruta, Narayan, Ankita, Le Rouzic, Valerie, Ansonoff, Michael, Pintar, John E., Pasternak, Gavril W.
Pubblicazione 2014

Synthesis and Characterization of Azido Aryl Analogs of IBNtxA for Radio-Photoaffinity Labeling Opioid Receptors in Cell Lines and in Mouse Brain

di Grinnell, Steven G., Uprety, Rajendra, Varadi, Andras, Subrath, Joan, Hunkele, Amanda, Pan, Ying Xian, Pasternak, Gavril W., Majumdar, Susruta
Pubblicato in Cell Mol Neurobiol (2020)

Novel 6β-acylaminomorphinans with analgesic activity

di Váradi, András, Hosztafi, Sándor, Rouzic, Valerie Le, Tóth, Gergő, Urai, Ákos, Noszál, Béla, Pasternak, Gavril W., Grinnell, Steven G., Majumdar, Susruta
Pubblicazione 2013

Mild, Pd-catalyzed stannylation of radioiodination targets

di Pickett, Julie E., Váradi, András, Palmer, Travis C., Grinnell, Steven G., Schrock, Joel M., Pasternak, Gavril W., Karimov, Rashad R., Majumdar, Susruta
Pubblicato in Bioorg Med Chem Lett (2015)

Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS

di Marrone, Gina F., Grinnell, Steven G., Lu, Zhigang, Rossi, Grace C., Le Rouzic, Valerie, Xu, Jin, Majumdar, Susruta, Pan, Ying-Xian, Pasternak, Gavril W.
Pubblicato in Proc Natl Acad Sci U S A (2016)

Regional heterogeneity of D2-receptor signaling in the dorsal striatum and nucleus accumbens

di Marcott, Pamela F, Gong, Sheng, Donthamsetti, Prashant, Grinnell, Steven G., Nelson, Melissa N., Newman, Amy H, Birnbaumer, Lutz, Martemyanov, Kirill A, Javitch, Jonathan A, Ford, Christopher P
Pubblicato in Neuron (2018)

Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants

di Grinnell, Steven G., Ansonoff, Michael, Marrone, Gina F., Lu, Zhigang, Narayan, Ankita, Xu, Jin, Rossi, Grace, Majumdar, Susruta, Pan, Ying-Xian, Bassoni, Daniel L., Pintar, John, Pasternak, Gavril
Pubblicato in Synapse (2016)

7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

di Kruegel, Andrew C., Uprety, Rajendra, Grinnell, Steven G., Langreck, Cory, Pekarskaya, Elizabeth A., Le Rouzic, Valerie, Ansonoff, Michael, Gassaway, Madalee M., Pintar, John E., Pasternak, Gavril W., Javitch, Jonathan A., Majumdar, Susruta, Sames, Dalibor
Pubblicato in ACS Cent Sci (2019)

The Behavioral Effects of the Antidepressant Tianeptine Require the Mu-Opioid Receptor

di Samuels, Benjamin Adam, Nautiyal, Katherine M, Kruegel, Andrew C, Levinstein, Marjorie R, Magalong, Valerie M, Gassaway, Madalee M, Grinnell, Steven G, Han, Jaena, Ansonoff, Michael A, Pintar, John E, Javitch, Jonathan A, Sames, Dalibor, Hen, René
Pubblicato in Neuropsychopharmacology (2017)

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2

di Váradi, András, Marrone, Gina F., Palmer, Travis C., Narayan, Ankita, Szabó, Márton R., Le Rouzic, Valerie, Grinnell, Steven G., Subrath, Joan J., Warner, Evelyn, Kalra, Sanjay, Hunkele, Amanda, Pagirsky, Jeremy, Eans, Shainnel O., Medina, Jessica M., Xu, Jin, Pan, Ying-Xian, Borics, Attila, Pasternak, Gavril W., McLaughlin, Jay P., Majumdar, Susruta
Pubblicato in J Med Chem (2016)

Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site

di Uprety, Rajendra, Che, Tao, Zaidi, Saheem A, Grinnell, Steven G, Varga, Balázs R, Faouzi, Abdelfattah, Slocum, Samuel T, Allaoa, Abdullah, Varadi, András, Nelson, Melissa, Bernhard, Sarah M, Kulko, Elizaveta, Le Rouzic, Valerie, Eans, Shainnel O, Simons, Chloe A, Hunkele, Amanda, Subrath, Joan, Pan, Ying Xian, Javitch, Jonathan A, McLaughlin, Jay P, Roth, Bryan L, Pasternak, Gavril W, Katritch, Vsevolod, Majumdar, Susruta
Pubblicato in eLife (2021)