Novel 6β-acylaminomorphinans with analgesic activity

Aminomorphinans are a relatively young class of opioid drugs among which substances of high in vitro efficacy and favorable in vivo action are found. We report the synthesis and pharmacological evaluation of novel 6β-acylaminomorphinans. 6β-Morphinamine and 6β-codeinamine were stereoselectively synt...

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Detalhes bibliográficos
Main Authors: Váradi, András, Hosztafi, Sándor, Rouzic, Valerie Le, Tóth, Gergő, Urai, Ákos, Noszál, Béla, Pasternak, Gavril W., Grinnell, Steven G., Majumdar, Susruta
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839676/
https://ncbi.nlm.nih.gov/pubmed/24103580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2013.09.031
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