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Novel 6β-acylaminomorphinans with analgesic activity
Aminomorphinans are a relatively young class of opioid drugs among which substances of high in vitro efficacy and favorable in vivo action are found. We report the synthesis and pharmacological evaluation of novel 6β-acylaminomorphinans. 6β-Morphinamine and 6β-codeinamine were stereoselectively synt...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839676/ https://ncbi.nlm.nih.gov/pubmed/24103580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2013.09.031 |
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