Towards understanding the structural basis of partial agonism at the dopamine D(3) receptor

Both dopamine D(3) receptor (D(3)R) partial agonists and antagonists have been implicated as potential medications for substance use disorders. In contrast to antagonists, partial agonists may cause fewer side effects since they maintain some dopaminergic tone and may be less disruptive to normal ne...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Michino, Mayako, Boateng, Comfort A., Donthamsetti, Prashant, Yano, Hideaki, Bakare, Oluyomi M., Bonifazi, Alessandro, Ellenberger, Michael P., Keck, Thomas M., Kumar, Vivek, Zhu, Clare, Verma, Ravi, Deschamps, Jeffrey R., Javitch, Jonathan A., Newman, Amy Hauck, Shi, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563258/
https://ncbi.nlm.nih.gov/pubmed/27983845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b01148
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