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Mutation of Three Residues in the Third Intracellular Loop of the Dopamine D(2) Receptor Creates an Internalization-defective Receptor

Arrestins mediate desensitization and internalization of G protein-coupled receptors and also direct receptor signaling toward heterotrimeric G protein-independent signaling pathways. We previously identified a four-residue segment (residues 212–215) of the dopamine D2 receptor that is necessary for...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Clayton, Cecilea C., Donthamsetti, Prashant, Lambert, Nevin A., Javitch, Jonathan A., Neve, Kim A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246117/
https://ncbi.nlm.nih.gov/pubmed/25336643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.605378
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