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Mutation of Three Residues in the Third Intracellular Loop of the Dopamine D(2) Receptor Creates an Internalization-defective Receptor
Arrestins mediate desensitization and internalization of G protein-coupled receptors and also direct receptor signaling toward heterotrimeric G protein-independent signaling pathways. We previously identified a four-residue segment (residues 212–215) of the dopamine D2 receptor that is necessary for...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246117/ https://ncbi.nlm.nih.gov/pubmed/25336643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.605378 |
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