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Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor
[Image: see text] G protein-coupled receptors (GPCRs) are the most common targets of drug discovery. However, the similarity between related GPCRs combined with the complex spatiotemporal dynamics of receptor activation in vivo has hindered drug development. Photopharmacology offers the possibility...
Guardado en:
| Publicado en: | J Am Chem Soc |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Chemical
Society
2021
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8227462/ https://ncbi.nlm.nih.gov/pubmed/34115935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c02586 |
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