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Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor
[Image: see text] G protein-coupled receptors (GPCRs) are the most common targets of drug discovery. However, the similarity between related GPCRs combined with the complex spatiotemporal dynamics of receptor activation in vivo has hindered drug development. Photopharmacology offers the possibility...
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| 發表在: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical
Society
2021
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8227462/ https://ncbi.nlm.nih.gov/pubmed/34115935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c02586 |
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