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Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor
[Image: see text] G protein-coupled receptors (GPCRs) are the most common targets of drug discovery. However, the similarity between related GPCRs combined with the complex spatiotemporal dynamics of receptor activation in vivo has hindered drug development. Photopharmacology offers the possibility...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2021
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8227462/ https://ncbi.nlm.nih.gov/pubmed/34115935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c02586 |
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