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Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors

G protein-coupled receptor (GPCR) signaling occurs in complex spatiotemporal patterns that are difficult to probe using standard pharmacological and genetic approaches. A powerful approach for dissecting GPCRs is to use light-controlled pharmacological agents that are tethered covalently and specifi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Levitz, Joshua, Broichhagen, Johannes, Leippe, Philipp, Konrad, David, Trauner, Dirk, Isacoff, Ehud Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410775/
https://ncbi.nlm.nih.gov/pubmed/28396447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619652114
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