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Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors
G protein-coupled receptor (GPCR) signaling occurs in complex spatiotemporal patterns that are difficult to probe using standard pharmacological and genetic approaches. A powerful approach for dissecting GPCRs is to use light-controlled pharmacological agents that are tethered covalently and specifi...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410775/ https://ncbi.nlm.nih.gov/pubmed/28396447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619652114 |
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