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Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand
[Image: see text] The covalent attachment of synthetic photoswitches is a general approach to impart light sensitivity onto native receptors. It mimics the logic of natural photoreceptors and significantly expands the reach of optogenetics. Here we describe a novel photoswitch design—the photoswitch...
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| Pubblicato in: | ACS Cent Sci |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2015
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4827557/ https://ncbi.nlm.nih.gov/pubmed/27162996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.5b00260 |
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