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Development of a New Photochromic Ion Channel Blocker via Azologization of Fomocaine

[Image: see text] Photochromic blockers of voltage gated ion channels are powerful tools for the control of neuronal systems with high spatial and temporal precision. We now introduce fotocaine, a new type of photochromic channel blocker based on the long-lasting anesthetic fomocaine. Fotocaine is r...

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Main Authors: Schoenberger, Matthias, Damijonaitis, Arunas, Zhang, Zinan, Nagel, Daniel, Trauner, Dirk
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102962/
https://ncbi.nlm.nih.gov/pubmed/24856540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500070w
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