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Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor
The analysis of cell signaling requires the rapid and selective manipulation of protein function. We have synthesized photoswitches that covalently modify target proteins and reversibly present and withdraw a ligand from its binding site due to photoisomerization of an azobenzene linker. We describe...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904147/ https://ncbi.nlm.nih.gov/pubmed/17578923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701274104 |
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