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Allosteric control of an ionotropic glutamate receptor with an optical switch

The precise regulation of protein activity is fundamental to life. The allosteric control of an active site by a remote regulatory binding site is a mechanism of regulation found across protein classes, from enzymes to motors to signaling proteins. We describe a general approach for manipulating all...

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Bibliografiske detaljer
Main Authors: Volgraf, Matthew, Gorostiza, Pau, Numano, Rika, Kramer, Richard H, Isacoff, Ehud Y, Trauner, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1447676/
https://ncbi.nlm.nih.gov/pubmed/16408092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio756
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