A Toolkit for Orthogonal and in vivo Optical Manipulation of Ionotropic Glutamate Receptors

The ability to optically manipulate specific neuronal signaling proteins with genetic precision paves the way for the dissection of their roles in brain function, behavior, and disease. Chemical optogenetic control with photoswitchable tethered ligands (PTLs) enables rapid, reversible and reproducib...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Levitz, Joshua, Popescu, Andrei T., Reiner, Andreas, Isacoff, Ehud Y.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735401/
https://ncbi.nlm.nih.gov/pubmed/26869877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00002
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