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A Toolkit for Orthogonal and in vivo Optical Manipulation of Ionotropic Glutamate Receptors

The ability to optically manipulate specific neuronal signaling proteins with genetic precision paves the way for the dissection of their roles in brain function, behavior, and disease. Chemical optogenetic control with photoswitchable tethered ligands (PTLs) enables rapid, reversible and reproducib...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Levitz, Joshua, Popescu, Andrei T., Reiner, Andreas, Isacoff, Ehud Y.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735401/
https://ncbi.nlm.nih.gov/pubmed/26869877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00002
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