Optical Control of Sphingosine-1-Phosphate Formation and Function

Sphingosine-1-phosphate (S1P) plays important roles as a signaling lipid in a variety of physiological and pathophysiological processes. S1P signals via a family of G protein-coupled receptors (S1P(1–5)) and intracellular targets. Here, we report on photoswitchable analogs of S1P and its precursor s...

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Publicado no:Nat Chem Biol
Main Authors: Morstein, Johannes, Hill, Rose Z., Novak, Alexander J. E., Feng, Suihan, Norman, Derek D., Donthamsetti, Prashant C., Frank, James A., Harayama, Takeshi, Williams, Benjamin M., Parrill, Abby L., Tigyi, Gabor J., Riezman, Howard, Isacoff, Ehud Y., Bautista, Diana M., Trauner, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428055/
https://ncbi.nlm.nih.gov/pubmed/31036923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0269-7
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