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Structure of the First Sphingosine 1-Phosphate Receptor
The sphingosine 1-phosphate receptor 1 (S1P(1)) and its ligand, sphingosine 1-phosphate (S1P), have now emerged as critical regulators of lymphocyte trafficking, vascular development and integrity, and immunity. S1P(1) is targeted by the phosphorylation product of fingolimod, which has been approved...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632326/ https://ncbi.nlm.nih.gov/pubmed/22623751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003160 |
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