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Activation mechanisms of the first sphingosine‐1‐phosphate receptor

Activation of the first sphingosine‐1‐phosphate receptor (S1PR(1)) promotes permeability of the blood brain barrier, astrocyte and neuronal protection, and lymphocyte egress from secondary lymphoid tissues. Although an agonist often activates the S1PR(1), the receptor exhibits high levels of basal a...

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Foilsithe in:Protein Sci
Main Authors: Caliman, Alisha D., Miao, Yinglong, McCammon, J. Andrew
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441409/
https://ncbi.nlm.nih.gov/pubmed/28370663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3165
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